Article
[Relapsed acute myeloid leukemia with Down syndrome showing long disease-free survival after bone marrow transplantation].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Feb 2009
Daifu Tomoo, Kato Itaru, Matubara Hiroshi, Abe Daisuke, Uryu Kumiko, Tokumasu Mayu, Umeda Katsutsugu, Watanabe Kenichiro, Izawa Kazusi, Asai Kouichi, Nakahata Tatsutoshi, Adachi Souichi
Abstract excerpt
We report a sixteen-year-old boy with Down syndrome and relapse of AML (M7), who has been in complete remission (CR) more than 12 months after bone marrow transplantation (BMT) from an HLA-matched sibling donor. Because monosomy 7 was detected at onset of AML and he experienced relapse after the treatment of AML 99 Down protocol, his prognosis was considered very poor. However, he achieved CR following...
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