Article
Association of the mitochondrial DNA 15497G/A polymorphism with obesity in a middle-aged and elderly Japanese population.
Human genetics - 1 Oct 2003
Okura Tomohiro, Koda Michiko, Ando Fujiko, Niino Naoakira, Tanaka Masashi, Shimokata Hiroshi
Abstract excerpt
Although polymorphism of the mitochondrial DNA 15497guanine/adenine (Mt15497G-->A) leads to the Gly251Ser amino acid replacement on human cytochrome b, it is unknown whether functional alteration of the mitochondrion is induced by the Gly251Ser replacement. To see if an association exists between the Mt15497G-->A polymorphism and obesity, we examined differences in body size, body composition, and regional body...
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