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Longevity-associated mitochondrial DNA 5178 C/A polymorphism is associated with fasting plasma glucose levels and glucose tolerance in Japanese men.

Mitochondrion - 1 Dec 2005

Kokaze Akatsuki, Ishikawa Mamoru, Matsunaga Naomi, Yoshida Masao, Makita Ryuji, Satoh Masao, Teruya Koji, Sekiguchi Kanako, Masuda Yumi, Harada Matsuko, Uchida Yoshiko, Takashima Yutaka

Abstract excerpt

Mitochondrial DNA 5178 cytosine/adenine (Mt5178 C/A) polymorphism is reportedly associated with longevity in the Japanese population, and the Mt5178A genotype may resist the onset of type 2 diabetes. To investigate whether Mt5178 C/A polymorphism is associated with glucose tolerance, we conducted a cross-sectional study using the 75-g oral glucose tolerance test (OGTT) in which non-diabetic Japanese male subjects...

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Identifiers

PMID: 16271520
DOI: 10.1016/j.mito.2005.09.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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