Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial GWA Analysis of Lipid Profile Identifies Genetic Variants to Be Associated with HDL Cholesterol and Triglyceride Levels.

PloS one - 1 Jan 2015

Flaquer Antònia, Rospleszcz Susanne, Reischl Eva, Zeilinger Sonja, Prokisch Holger, Meitinger Thomas, Meisinger Christa, Peters Annette, Waldenberger Melanie, Grallert Harald, Strauch Konstantin

Abstract excerpt

It has been suggested that mitochondrial dysfunction has an influence on lipid metabolism. The fact that mitochondrial defects can be accumulated over time as a normal part of aging may explain why cholesterol levels often are altered with age. To test the hypothesis whether mitochondrial variant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cholesterol, HDL
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Mitochondrial

Share to Germany

Share to Lipid Metabolism

Share to Mitochondria

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 25945934
DOI: 10.1371/journal.pone.0126294
PMCID: PMC4422732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25945934-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial GWA Analysis of Lipid Profile Identifies Genetic Variants to Be Associated with HDL Cholesterol and Triglyceride Levels.PMID 25945934Read ↗

Mitochondrial genetic variants identified to be associated with BMI in adults.Semantic proximity Read ↗

Mitochondrial DNA Mutations Linking Leigh Syndrome and Carotid Atherosclerosis: A Study of Shared Genetic PathwaysSemantic proximity Read ↗

The association of mitochondrial DNA 5178 C > a polymorphism with plasma lipid levels among three ethnic groups.Semantic proximity Read ↗

ASSOCIATION ANALYSIS OF MITOCHONDRIAL HETEROPLASMIC VARIANTS AND CARDIOMETABOLIC TRAITSSemantic proximity Read ↗

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studiesSemantic proximity Read ↗

Association of mitochondrial genetic variation with carotid atherosclerosis.Semantic proximity Read ↗

[Analysis of mitochondrial haplogroups in persons with subclinical atherosclerosis based on high-throughput mtDNA sequencing].Semantic proximity Read ↗

MTTP-297H polymorphism reduced serum cholesterol but increased risk of non-alcoholic fatty liver disease-a cross-sectional study.Semantic proximity Read ↗

Mutation C3256T of mitochondrial genome in white blood cells: novel genetic marker of atherosclerosis and coronary heart disease.Semantic proximity Read ↗

Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.Semantic proximity Read ↗

Association of mutations in the mitochondrial genome with the subclinical carotid atherosclerosis in women.Semantic proximity Read ↗

JCL roundtable: Lessons from genetic variants altering lipoprotein metabolism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.