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Genetic Analysis of the Clonal Origin of Regenerating Mouse Spermatogenesis Following Transplantation1

1 Dec 2003

Abstract excerpt

Spermatogonial transplantation provides a straightforward approach to quantify spermatogonial stem cells (SSCs). Because donor-derived spermatogenesis is regenerated in the form of distinct colonies, the number of functional SSCs can be obtained by simply counting the number of colonies established in recipient testes. However, this approach is legitimate only when one colony arises from one stem cell (one...

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PMID: 12904317
DOI: 10.1095/biolreprod.103.019273

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