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Establishment of a Short-Term In Vitro Assay for Mouse Spermatogonial Stem Cells1

9 Aug 2007

Abstract excerpt

Spermatogonial stem cells (SSCs) are responsible for life-long, daily production of male gametes and for the transmission of genetic information to the next generation. Unequivocal detection of SSCs has relied on spermatogonial transplantation, in which functional SSCs are analyzed qualitatively and quantitatively based on their regenerative capacity. However, this technique has some significant limitations. For...

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PMID: 17687116
DOI: 10.1095/biolreprod.107.063057

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