Article
Genetic influences in mouse spermatogonial stem cell self-renewal.
The Journal of reproduction and development - 1 Feb 2010
Kanatsu-Shinohara Mito, Ogonuki Narumi, Miki Hiromi, Inoue Kimiko, Morimoto Hiroko, Takashima Seiji, Ogura Atsuo, Shinohara Takashi
Abstract excerpt
Spermatogonial stem cells (SSCs) are slowly dividing cells that undergo self-renewal division to support spermatogenesis. Although the effects of genetic background in stem cell self-renewal have been well studied in hematopoietic stem cells, little is known about its effect on stem cells in other self-renewing tissues, including SSCs. To examine whether genetic factors are involved in regulation of SSC...
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