Article
[Mutant thiopurine S-methyltransferase alleles among Jing Chinese in Guangxi province].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2003
Zhang Jian-ping, Huang Min, Guan Yong-yuan, Xu An-long, Wu Jue-heng
Abstract excerpt
OBJECTIVE: To investigate the mutant alleles of thiopurine S-methyltransferase (TPMT) among Jing Chinese. METHODS: Polymerse chain reaction-single strand conformation polymorphism (PCR-SSCP) techniques were developed for assaying exons 5, 7 and 10 of the TPMT gene respectively and were used to detect mutant TPMT alleles among Jing Chinese. RESULTS: Two cases of TPMT*3C (A719G) heterozygotes were identified in 103...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
