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Article

[Relationships between thiopurine methyltransferase gene polymorphisms and its enzymatic activity].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jun 2006

Ma Xiao-Li, Wu Min-Yuan, Hu Ya-Mei, Zu Ping, Li Zhi-Gang

Abstract excerpt

OBJECTIVE: To investigate the relationship between the thiopurine methytransferase (TPMT) gene polymorphisms and its enzymatic activity, and to clarify the significance of TPMT activity and gene polymorphisms on individualized therapy with thiopurines. METHODS: The TPMT activity and gene polymorphisms were determined in an unrelated population of 250 Chinese healthy blood donors, 100 cords blood and 280 patients...

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Source

Identifiers

PMID: 17152495

Genes

TPMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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