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Article

Two functional heads are required for full activation of smooth muscle myosin.

The Journal of biological chemistry - 8 Aug 2003

Li Xiang-dong, Ikebe Mitsuo

Abstract excerpt

The motor activity of smooth muscle myosin II is regulated by the regulatory light chain phosphorylation, but it is not understood how phosphorylation activates motor activity. To address this question, we produced asymmetric heavy meromyosin (HMM), which is composed of a wild-type (WT) heavy cha...

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Identifiers

PMID: 12759357
DOI: 10.1074/jbc.M301784200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12759357-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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