Article
Differential binding of ligands to the apolipoprotein E receptor 2.
Biochemistry - 12 Aug 2003
Andersen Olav M, Benhayon David, Curran Tom, Willnow Thomas E
Abstract excerpt
Apolipoprotein E receptor 2 (apoER2) is an important participant in the Reelin signaling pathway that directs cell positioning during embryogenesis. ApoER2 is a cell surface molecule that elicits intracellular signal transduction through binding of Reelin. The structural requirements for Reelin binding to apoER2 and the receptor domains involved in this process are unclear at present. Using a series of receptor...
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