Article
Clinically relevant interpretation of genotype for resistance to abacavir.
AIDS (London, England) - 15 Aug 2003
Brun-Vézinet Françoise, Descamps Diane, Ruffault Annick, Masquelier Bernard, Calvez Vincent, Peytavin Gilles, Telles Fabienne, Morand-Joubert Laurence, Meynard Jean-Luc, Vray Muriel, Costagliola Dominique
Abstract excerpt
OBJECTIVE: To develop a stepwise methodology for the development and validation of clinically relevant genotypic score for resistance to antiretroviral drugs and to apply this approach to the genotypic resistance to abacavir. METHODS: All patients having received abacavir during the Narval trial were included in this study. The impact of each nucleoside analogue resistance mutation on the virologic response to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
