Article
A genotypic drug resistance interpretation algorithm that significantly predicts therapy response in HIV-1-infected patients.
Antiviral therapy - 1 Jun 2002
Van Laethem Kristel, De Luca Andrea, Antinori Andrea, Cingolani Antonella, Perna Carlo Federico, Vandamme Anne-Mieke
Abstract excerpt
OBJECTIVES: The development of a genotypic drug resistance interpretation algorithm, and the evaluation of its power to predict therapy outcome. DESIGN: A rule-based algorithm was established by an individual expert and was based on published and in-house results, independently from the data of the patients used in this evaluation. The predictive value of the algorithm for virological outcomes was retrospectively...
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