Article
Genotypic determinants of the virological response to tenofovir disoproxil fumarate in nucleoside reverse transcriptase inhibitor-experienced patients.
Antiviral therapy - 1 Jun 2004
Masquelier Bernard, Tamalet Catherine, Montès Brigitte, Descamps Diane, Peytavin Gilles, Bocket Laurence, Wirden Marc, Izopet Jacques, Schneider Véronique, Ferré Virginie, Ruffault Annick, Palmer Pierre, Trylesinski Aldo, Miller Michael, Brun-Vézinet Françoise, Costagliola Dominique
Abstract excerpt
OBJECTIVE: To assess the genotypic determinants of the virological response to tenofovir disoproxil fumarate (TDF) in a multicentre cohort of antiretroviral (ARV)-experienced patients receiving TDF as a part of a salvage therapy. METHODS: HIV-1 genotype was assessed at baseline in a subgroup of 161 patients of the French expanded access program receiving a stable TDF-including regimen for 3 months or more....
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