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Article

Alterations in beta-amyloid production and deposition in brain regions of two transgenic models.

Neurobiology of aging - 1 Sept 2003

Lehman Emily J H, Kulnane Laura Shapiro, Lamb Bruce T

Abstract excerpt

Mutations in the amyloid precursor protein (APP) gene are associated with altered production and deposition of amyloid beta (Abeta) peptide in the Alzheimer's disease (AD) brain. The pathways that regulate APP processing, Abeta production and Abeta deposition in different tissues and brain regions remain unclear. To address this, we examined levels of various APP processing products as well as Abeta deposition in...

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Identifiers

PMID: 12885572
DOI: 10.1016/s0197-4580(02)00153-7

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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