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Article

Formation of beta-amyloid protein deposits in brains of transgenic mice.

Nature - 18 Jul 1991

Quon D, Wang Y, Catalano R, Scardina J M, Murakami K, Cordell B

Abstract excerpt

Deposits of beta-amyloid are one of the main pathological characteristics of Alzheimer's disease. The beta-amyloid peptide constituent (relative molecular mass 4,200) of the deposits is derived from the beta-amyloid precursor protein (beta-APP) which is expressed in several different isoforms. The two most prevalent beta-APP isoforms are distinguished by either the presence (beta-APP751) or absence (beta-APP695)...

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Source

Identifiers

PMID: 1906990
DOI: 10.1038/352239a0

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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