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Article

Investigation of Rare Single-Nucleotide PCDH15 Variants in Schizophrenia and Autism Spectrum Disorders.

PloS one - 1 Jan 2016

Ishizuka Kanako, Kimura Hiroki, Wang Chenyao, Xing Jingrui, Kushima Itaru, Arioka Yuko, Oya-Ito Tomoko, Uno Yota, Okada Takashi, Mori Daisuke, Aleksic Branko, Ozaki Norio

Abstract excerpt

Both schizophrenia (SCZ) and autism spectrum disorders (ASD) are neuropsychiatric disorders with overlapping genetic etiology. Protocadherin 15 (PCDH15), which encodes a member of the cadherin super family that contributes to neural development and function, has been cited as a risk gene for neuropsychiatric disorders. Recently, rare variants of large effect have been paid attention to understand the...

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Source

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Identifiers

PMID: 27058588
DOI: 10.1371/journal.pone.0153224
PMCID: PMC4825995

Genes

PCDH15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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