Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of protocadherin alpha gene enhancer polymorphism in bipolar disorder and schizophrenia.

Schizophrenia research - 1 Jul 2008

Pedrosa Erika, Stefanescu Radu, Margolis Benjamin, Petruolo Oriana, Lo Yungtai, Nolan Karen, Novak Tomas, Stopkova Pavla, Lachman Herbert M

Abstract excerpt

Cadherins and protocadherins are cell adhesion proteins that play an important role in neuronal migration, differentiation and synaptogenesis, properties that make them targets to consider in schizophrenia (SZ) and bipolar disorder (BD) pathogenesis. Consequently, allelic variation occurring in protocadherin and cadherin encoding genes that map to regions of the genome targeted in SZ and BD linkage studies are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Bipolar Disorder

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cadherins

Share to Chromosomes, Human, Pair 5

Share to Enhancer Elements, Genetic

Share to Multigene Family

Share to Oligonucleotide Array Sequence Analysis

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 18508241
DOI: 10.1016/j.schres.2008.04.013
PMCID: PMC2862380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of protocadherin alpha gene enhancer polymorphism in bipolar disorder and schizophrenia.PMID 18508241Read ↗

Variation in the protocadherin gamma A gene cluster.Semantic proximity Read ↗

Screening the human protocadherin 8 (PCDH8) gene in schizophrenia.Semantic proximity Read ↗

ProtocadherinX/Y, a candidate gene-pair for schizophrenia and schizoaffective disorder: a DHPLC investigation of genomic sequence.Semantic proximity Read ↗

Identification and characterization of coding single-nucleotide polymorphisms within human protocadherin-alpha and -beta gene clusters.Semantic proximity Read ↗

Novel Ultra-Rare Exonic Variants Identified in a Founder Population Implicate Cadherins in SchizophreniaSemantic proximity Read ↗

The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.Semantic proximity Read ↗

The role of cadherin genes in five major psychiatric disorders: A literature update.Semantic proximity Read ↗

Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia.Semantic proximity Read ↗

Cadherins and neuropsychiatric disorders.Semantic proximity Read ↗

The role and expression of the protocadherin-alpha clusters in the CNS.Semantic proximity Read ↗

Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders.Semantic proximity Read ↗

Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.