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Article

TP53 mutations and S-phase fraction but not DNA-ploidy are independent prognostic indicators in laryngeal squamous cell carcinoma.

Journal of cellular physiology - 1 Jan 2006

Russo Antonio, Corsale Simona, Agnese Valentina, Macaluso Marcella, Cascio Sandra, Bruno Loredana, Surmacz Eva, Dardanoni Gabriella, Valerio Maria Rosaria, Vieni Salvatore, Restivo Salvatore, Fulfaro Fabio, Tomasino Rosa Maria, Gebbia Nicola, Bazan Viviana

Abstract excerpt

To prospectively evaluate the prognostic significance of TP53, H-, K-, and N-Ras mutations, DNA-ploidy and S-phase fraction (SPF) in patients affected by locally advanced laryngeal squamous cell carcinoma (LSCC). Eight-one patients (median follow-up was 71 months) who underwent resective surgery...

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Share to Carcinoma, Squamous Cell
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, ras

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Share to Polymorphism, Single-Stranded Conformational

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Identifiers

PMID: 15965904
DOI: 10.1002/jcp.20447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15965904-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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