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Article

PNAS-4 expression and its relationship to p53 in colorectal cancer.

Molecular biology reports - 1 Jan 2012

Zhou Bin, Yan Hui, Li Yuan, Wang Rong, Chen Keling, Zhou Zongguang, Sun Xiaofeng

Abstract excerpt

PNAS-4 is a novel pro-apoptotic protein activated during the early response to DNA damage; however, the molecular mechanisms and pathways regulating PNAS-4 expression in tumors are not well understood. We hypothesized that PNAS-4 is a p53 down-stream target gene and designed this study. We searched online for putative p53-binding sites in the entire PNAS-4 gene and did not find any corresponding information. In...

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Share to Apoptosis Regulatory Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21556770
DOI: 10.1007/s11033-011-0732-3

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