Protein expression of NF-kappaB in human colorectal adenocarcinoma.

Abstract excerpt

NF-kappaB is a transcription factor believed to mediate a cellular survival response following the apoptotic stimulus TNF-alpha. To clarify the role of NF-kappaB in colorectal cancer, we investigated the relationship of NF-kappaB expression by immunohistochemistry with clinicopathological variables, and other factors including apoptotic index, bcl-2 expression, p53 and K-ras mutations in 138 colorectal...

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