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Article

Cyclo-oxygenase 2 function is essential for bone fracture healing.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2002

Simon Ann Marie, Manigrasso Michaele Beth, O'Connor J Patrick

Abstract excerpt

Despite the molecular and histological similarities between fetal bone development and fracture healing, inflammation is an early phase of fracture healing that does not occur during development. Cyclo-oxygenase 2 (COX-2) is induced at inflammation sites and produces proinflammatory prostaglandins. To determine if COX-2 functions in fracture healing, rats were treated with COX-2-selective nonsteroidal...

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Source

Identifiers

PMID: 12054171
DOI: 10.1359/jbmr.2002.17.6.963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cyclo-oxygenase 2 function is essential for bone fracture healing.PMID 12054171Read ↗

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