Article
Protein kinase C beta (PRKCB1) and pigment epithelium derived factor (PEDF) gene polymorphisms and diabetic retinopathy in a south Indian cohort.
Ophthalmic genetics - 1 Mar 2010
Uthra Satagopan, Raman Rajiv, Mukesh Bickol N, Rajkumar Samuel A, Kumari Padmaja R, Lakshmipathy Praveena, Gnanamoorthy Perumal, Sharma Tarun, McCarty Catherine A, Kumaramanickavel Govindasamy
Abstract excerpt
PURPOSE: Polymorphisms in protein kinase C beta (PRKCB1) and pigment epithelium derived factor (PEDF) genes have been associated with diabetic nephropathy and retinopathy respectively. Association of promoter polymorphisms-1504C/T and-1440G/T in PRKCB1 gene and sequence variations in exon 4 of PEDF gene are studied with diabetic retinopathy (DR) in a south Indian population based cohort. METHODS: Type 2 diabetic...
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