Article
A mutated CCR5 gene may have favorable prognostic implications in MS.
Neurology - 22 Jul 2003
Kantor Rami, Bakhanashvili Mary, Achiron Anat
Abstract excerpt
The authors investigated the association between Delta32CCR5, a mutated allele of the chemokine receptor CCR5, and disease progression in 256 patients with multiple sclerosis (MS). The mutated allele frequency in the study cohort was 7.4%, similar to that reported in the general Israeli population. Progression to disability was prolonged in Delta32CCR5 homozygotes and heterozygotes compared with MS patients with...
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