Article
Critical role of RelB serine 368 for dimerization and p100 stabilization.
The Journal of biological chemistry - 3 Oct 2003
Maier Harald Jakob, Marienfeld Ralf, Wirth Thomas, Baumann Bernd
Abstract excerpt
In mature B cells RelB-containing complexes are constitutively present in the nucleus, and they are less susceptible to inhibitory kappaB proteins. In most other cell types inhibitory kappaB proteins prevent nuclear translocation and activation of NFkappaB. We reasoned that this characteristic might be because of post-translational modifications of RelB. In Drosophila, signal-dependent phosphorylation of the Rel...
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