Article
On the use of permutation in and the performance of a class of nonparametric methods to detect differential gene expression.
Bioinformatics (Oxford, England) - 22 Jul 2003
Pan Wei
Abstract excerpt
MOTIVATION: Recently a class of nonparametric statistical methods, including the empirical Bayes (EB) method, the significance analysis of microarray (SAM) method and the mixture model method (MMM), have been proposed to detect differential gene expression for replicated microarray experiments conducted under two conditions. All the methods depend on constructing a test statistic Z and a so-called null statistic...
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