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Article

A close examination of double filtering with fold change and T test in microarray analysis.

BMC bioinformatics - 8 Dec 2009

Zhang Song, Cao Jing

Abstract excerpt

BACKGROUND: Many researchers use the double filtering procedure with fold change and t test to identify differentially expressed genes, in the hope that the double filtering will provide extra confidence in the results. Due to its simplicity, the double filtering procedure has been popular with applied researchers despite the development of more sophisticated methods. RESULTS: This paper, for the first time to...

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PMID: 19995439
DOI: 10.1186/1471-2105-10-402
PMCID: PMC2801685

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