Article
A Bayesian determination of threshold for identifying differentially expressed genes in microarray experiments.
Statistics in medicine - 30 Sept 2006
Chen Jie, Sarkar Sanat K
Abstract excerpt
The original definitions of false discovery rate (FDR) and false non-discovery rate (FNR) can be understood as the frequentist risks of false rejections and false non-rejections, respectively, conditional on the unknown parameter, while the Bayesian posterior FDR and posterior FNR are conditioned on the data. From a Bayesian point of view, it seems natural to take into account the uncertainties in both the...
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