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Article

Activity-dependent remodeling of presynaptic inputs by postsynaptic expression of activated CaMKII.

Neuron - 17 Jul 2003

Pratt Kara G, Watt Alanna J, Griffith Leslie C, Nelson Sacha B, Turrigiano Gina G

Abstract excerpt

Competitive synaptic remodeling is an important feature of developmental plasticity, but the molecular mechanisms remain largely unknown. Calcium/calmodulin-dependent protein kinase II (CaMKII) can induce postsynaptic changes in synaptic strength. We show that postsynaptic CaMKII also generates structural synaptic rearrangements between cultured cortical neurons. Postsynaptic expression of activated CaMKII...

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Source

Identifiers

PMID: 12873384
DOI: 10.1016/s0896-6273(03)00422-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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