Article
Surface salt bridges modulate DNA wrapping by the type II DNA-binding protein TF1.
Biochemistry - 29 Jul 2003
Grove Anne
Abstract excerpt
The histone-like protein HU is involved in compaction of the bacterial genome. Up to 37 bp of DNA may be wrapped about some HU homologues in a process that has been proposed to depend on a linked disruption of surface salt bridges that liberates cationic side chains for interaction with the DNA. Despite significant sequence conservation between HU homologues, binding sites from 9 to 37 bp have been reported. TF1,...
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