Article
[Antigenic analysis of the common recombinant mutant types of HBsAg].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Mar 2003
Bai Yu, Xia Guo-ling, Jia Zhi-yuan, Cong Yu, Wang Xiao-li, Guo Min-zhuo, Zhan Mei-yun
Abstract excerpt
BACKGROUND: To study the difference between the mutant types and the wild type of HBsAg on the binding efficiency with antibodies in order to find some methods to detect the mutants. METHODS: The recombinant wild type of HBsAg and the mutants including 145 R, 133 T, 126 S, 141 E, 126 S+133 T, 126 S+133 T+145 R and 126 S+133 T+141 E were cloned, respectively. Then the expression vector containing the wild or...
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