Article
[Expression of recombinant inserting mutants of HBsAg in vitro and its antigenic analysis].
Zhonghua yi xue za zhi - 1 Feb 1999
Gu B, Ren H, Zhang D
Abstract excerpt
OBJECTIVE: To study the immunological characteristics of two inserting variants of HBsAg as further to elucidate the role of inserting mutants in the development of HBsAg-negative chronic hepatitis B. METHODS: The inserting mutants of HBsAg were constructed by PCR-mediated mutagenesis in vitro. E...
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