Article
HLA-DRB1 allele and autoantibody profiles in Japanese patients with inclusion body myositis.
PloS one - 1 Jan 2020
Oyama Munenori, Ohnuki Yuko, Inoue Michio, Uruha Akinori, Yamashita Satoshi, Yutani Sachiko, Tanboon Jantima, Nakahara Jin, Suzuki Shingo, Shiina Takashi, Nishino Ichizo, Suzuki Shigeaki
Abstract excerpt
INTRODUCTION: Inclusion body myositis (IBM) is an idiopathic inflammatory myopathy, characterized by unique clinical features including finger flexor and quadriceps muscle weakness and a lack of any reliable treatment. The human leukocyte antigen (HLA)-DRB1 allele and autoantibody profiles in Japanese IBM patients have not been fully elucidated. METHODS: We studied 83 Japanese IBM patients with a mean age of 69...
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