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Article

Arginine residues in the active site of human phenol sulfotransferase (SULT1A1).

The Journal of biological chemistry - 19 Sept 2003

Chen Guangping, Chen Xinrong

Abstract excerpt

Cytosolic sulfotransferases (STs) catalyze the sulfation of hydroxyl containing compounds. Human phenol sulfotransferase (SULT1A1) is the major human ST that catalyzes the sulfation of simple phenols. Because of its broad substrate specificity and lack of endogenous substrates, the biological function of SULT1A1 is believed to be an important detoxification enzyme. In this report, amino acid modification,...

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Identifiers

PMID: 12867416
DOI: 10.1074/jbc.M306045200
PMCID: PMC3118444

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