Article
Expression of classical cadherins in thyroid development: maintenance of an epithelial phenotype throughout organogenesis.
Endocrinology - 1 Aug 2003
Fagman H, Grände M, Edsbagge J, Semb H, Nilsson M
Abstract excerpt
The long distance between the final location of the thyroid gland in front of the trachea and the site of embryological specification at the tongue base suggests that active migration of the thyroid progenitor cells is required. During embryogenesis, similar morphogenetic events often involve epithelial to mesenchymal transition (EMT), which promotes the acquisition of a migrating phenotype. EMT is characterized...
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