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Article

Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cells.

BMC molecular biology - 30 Sept 2014

Filippone Maria Grazia, Di Palma Tina, Lucci Valeria, Zannini Mariastella

Abstract excerpt

BACKGROUND: The transcription factor Pax8 is expressed during thyroid development and is involved in the morphogenesis of the thyroid gland and maintenance of the differentiated phenotype. In particular, Pax8 has been shown to regulate genes that are considered markers of thyroid differentiation. Recently, the analysis of the gene expression profile of FRTL-5 differentiated thyroid cells after the silencing of...

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Source

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Identifiers

PMID: 25270402
DOI: 10.1186/1471-2199-15-21
PMCID: PMC4200477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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