Article
The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus.
Clinical endocrinology - 1 Aug 2003
Roussel Ronan, Reis André F, Dubois-Laforgue Danièle, Bellanné-Chantelot Christine, Timsit José, Velho Gilberto
Abstract excerpt
OBJECTIVE: A single nucleotide polymorphism (A1220G; N363S) in exon 2 of the glucocorticoid receptor gene (NR3C1), associated with increased sensitivity to glucocorticoids, was shown to be associated with obesity in nondiabetic subjects. Here, we investigated the impact of this variant on traits...
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