Article
Marker-assisted congenic screening (MACS): a database tool for the efficient production and characterization of congenic lines.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2003
Collins Stephan C, Wallis Robert H, Wallace Karin, Bihoreau Marie Thérèse, Gauguier Dominique
Abstract excerpt
Over the past decades, genetic studies in rodent models of human multifactorial disorders have led to the detection of numerous chromosomal regions associated with disease phenotypes. Owing to the complex control of these phenotypes and the size of the disease loci, identifying the underlying genes requires further analyses in new original models, including chromosome substitution (consomic) and congenic lines,...
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