Article
Phenotypic consequences of beta1-tubulin expression and MAP4 decoration of microtubules in adult cardiocytes.
American journal of physiology. Heart and circulatory physiology - 1 Nov 2003
Takahashi Masaru, Shiraishi Hirokazu, Ishibashi Yuji, Blade Kristie L, McDermott Paul J, Menick Donald R, Kuppuswamy Dhandapani, Cooper George
Abstract excerpt
In pressure-overload cardiac hypertrophy, microtubule network densification is one cause of contractile dysfunction. Cardiac transcriptional upregulation of beta1-tubulin rather than the constitutive beta4-tubulin and of microtubule-associated protein (MAP)4 accompanies hypertrophy, with extensiv...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
