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Article

Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7.

The EMBO journal - 15 Jul 2003

Fassati Ariberto, Görlich Dirk, Harrison Ian, Zaytseva Lyubov, Mingot José-Manuel

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1), like other lentiviruses, can infect non-dividing cells. This property depends on the active nuclear import of its intracellular reverse transcription complex (RTC). We have studied nuclear import of purified HIV-1 RTCs in primary macrophages and found that importin 7, an import receptor for ribosomal proteins and histone H1, is involved in the process. Nuclear import...

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Identifiers

PMID: 12853482
DOI: 10.1093/emboj/cdg357
PMCID: PMC165627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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