Article
Interaction of human immunodeficiency virus type 1 integrase with cellular nuclear import receptor importin 7 and its impact on viral replication.
The Journal of biological chemistry - 4 May 2007
Ao Zhujun, Huang Guanyou, Yao Han, Xu Zaikun, Labine Meaghan, Cochrane Alan W, Yao Xiaojian
Abstract excerpt
Similar to all other viruses, human immunodeficiency virus type 1 (HIV-1) depends heavily on cellular factors for its successful replication. In this study we have investigated the interaction of HIV-1 integrase (IN) with several host nuclear import factors using co-immunoprecipitation assays. Ou...
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