Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emergence of mutant HIV reverse transcriptase conferring resistance to AZT.

Journal of enzyme inhibition - 1 Jan 1992

Richman D D

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Drug Resistance, Microbial
Share to HeLa Cells
Share to HIV

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HIV Infections

Share to RNA-Directed DNA Polymerase

Share to Time Factors

Share to Zidovudine

Source

Identifiers

PMID: 1285303
DOI: 10.3109/14756369209041356

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Emergence of mutant HIV reverse transcriptase conferring resistance to AZT.PMID 1285303Read ↗

Evolution of AZT resistance in HIV-1: the 41-70 intermediate that is not observed in vivo has a replication defect.Semantic proximity Read ↗

Potential Mechanism for Sustained Antiretroviral Efficacy of AZT-3TC Combination TherapySemantic proximity Read ↗

Characterization of reverse transcriptase activity and susceptibility to other nucleosides of AZT-resistant variants of HIV-1. Results from the Canadian AZT Multicentre Study.Semantic proximity Read ↗

Emergence and genetic evolution of HIV-1 variants with mutations conferring resistance to multiple reverse transcriptase and protease inhibitors.Semantic proximity Read ↗

3'-Azido-3'-deoxythymidine (AZT) mediates cross-resistance to nucleoside analogs in the case of AZT-resistant human immunodeficiency virus type 1 variants.Semantic proximity Read ↗

Development and significance of nucleoside drug resistance in infection caused by the human immunodeficiency virus type 1.Semantic proximity Read ↗

Development and application of a genotypic AZT resistance assay: quantitative assessment of the resistance profile of clinical samples and the relative predictive ability of a resistance index.Semantic proximity Read ↗

Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3'-azido-3'-dideoxythymidine.Semantic proximity Read ↗

In vitro study of resistance-associated genotypic mutations to nucleoside analogs.Semantic proximity Read ↗

A Novel Polymorphism at Codon 333 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Can Facilitate Dual Resistance to Zidovudine and l -2′,3′-Dideoxy-3′-ThiacytidineSemantic proximity Read ↗

Generation of nucleoside-resistant variants of HIV-1 by in vitro selection in the presence of AZT or DDI but no by combinations.Semantic proximity Read ↗

Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.