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Article

Variance-component analysis of obesity in type 2 diabetes confirms loci on chromosomes 1q and 11q.

Obesity research - 1 Nov 2003

van Tilburg Jonathan H O, Sandkuijl Lodewijk A, Strengman Eric, Pearson Peter L, van Haeften Timon W, Wijmenga Cisca

Abstract excerpt

To study genetic loci influencing obesity in nuclear families with type 2 diabetes, we performed a genome-wide screen with 325 microsatellite markers that had an average spacing of 11 cM and a mean heterozygosity of approximately 75% covering all 22 autosomes. Genotype data were obtained from 562 individuals from 178 families from the Breda Study Cohort. These families were determined to have at least two members...

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Identifiers

PMID: 14627748
DOI: 10.1038/oby.2003.175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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