Article
Modulation of blood pressure and obesity with the dopamine D2 receptor gene TaqI polymorphism.
Hypertension (Dallas, Tex. : 1979) - 1 Aug 2000
Thomas G N, Tomlinson B, Critchley J A
Abstract excerpt
Pharmacological data suggest that obesity and blood pressure (BP) may be modulated through the dopamine D2 receptor (DD2R), which may represent an underlying mechanism that links these conditions. A TAQ:I polymorphism near the DD2R gene has been associated with indices of obesity in white populations. We compared anthropometric and fasting plasma biochemical parameters between 209 nondiabetic hypertensive and 174...
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