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Article

Cellular prion protein promotes Brucella infection into macrophages.

The Journal of experimental medicine - 7 Jul 2003

Watarai Masahisa, Kim Suk, Erdenebaatar Janchivdorj, Makino Sou-ichi, Horiuchi Motohiro, Shirahata Toshikazu, Sakaguchi Suehiro, Katamine Shigeru

Abstract excerpt

The products of the Brucella abortus virB gene locus, which are highly similar to conjugative DNA transfer system, enable the bacterium to replicate within macrophage vacuoles. The replicative phagosome is thought to be established by the interaction of a substrate of the VirB complex with macrophages, although the substrate and its host cellular target have not yet been identified. We report here that Hsp60, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12847134
DOI: 10.1084/jem.20021980
PMCID: PMC2196088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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