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Article

Smooth and rough lipopolysaccharide phenotypes of Brucella induce different intracellular trafficking and cytokine/chemokine release in human monocytes.

Journal of leukocyte biology - 1 Dec 2003

Rittig Michael G, Kaufmann Andreas, Robins Adrian, Shaw Barry, Sprenger Hans, Gemsa Diethard, Foulongne Vincent, Rouot Bruno, Dornand Jacques

Abstract excerpt

Virulence of the intracellular pathogen Brucella for humans is mainly associated with its lipopolysaccharide (LPS) phenotype, with smooth LPS phenotypes generally being virulent and rough ones not. The reason for this association is not quite understood. We now demonstrate by flow cytometry, elec...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12960272
DOI: 10.1189/jlb.0103015

Genes

MIP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12960272-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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