Article
Release of periplasmic proteins of Brucella suis upon acidic shock involves the outer membrane protein Omp25.
Infection and immunity - 1 Oct 2004
Boigegrain Rose-Anne, Salhi Imed, Alvarez-Martinez Maria-Teresa, Machold Jan, Fedon Yann, Arpagaus Martine, Weise Christoph, Rittig Michael, Rouot Bruno
Abstract excerpt
The survival and replication of Brucella in macrophages is initially triggered by a low intraphagosomal pH. In order to identify proteins released by Brucella during this early acidification step, we analyzed Brucella suis conditioned medium at various pH levels. No significant proteins were released at pH 4.0 in minimal medium or citrate buffer, whereas in acetate buffer, B. suis released a substantial amount of...
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