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Article

Nucleomodulin BspJ as an effector promotes the colonization ofBrucella abortusin the host

26 Nov 2021

Abstract excerpt

Background: Brucella infection induces brucellosis, a zoonotic disease.The intracellular circulation process and virulence of Brucella mainly depend on its type IV secretion system (T4SS) expressing secretory effectors.Secreted protein BspJ is a nucleomodulin of Brucella that invades the host cell nucleus.BspJ mediates host energy synthesis and apoptosis through interaction with proteins.However, the mechanism of...

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PMID: 34841746
DOI: 10.4142/jvs.21224

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