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Article

CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells.

The Journal of biological chemistry - 19 Sept 2003

Kojima Hiroshi, Kanada Hirotaka, Shimizu Seiichi, Kasama Emi, Shibuya Kazuko, Nakauchi Hiromitsu, Nagasawa Toshiro, Shibuya Akira

Abstract excerpt

Platelet adhesion to vascular endothelial cells is a pathophysiologically relevant cell-to-cell interaction. However, the mechanisms underlying this cellular interaction are incompletely understood. In search of the ligand for CD226 adhesion molecule expressed on platelets, we found that human umbilical vein endothelial cells (HUVEC) express significant amount of putative CD226 ligand. We demonstrated that...

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Identifiers

PMID: 12847109
DOI: 10.1074/jbc.M300702200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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