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Article

Activated platelets induce tissue factor expression on human umbilical vein endothelial cells by ligation of CD40.

Thrombosis and haemostasis - 1 Dec 1998

Slupsky J R, Kalbas M, Willuweit A, Henn V, Kroczek R A, Müller-Berghaus G

Abstract excerpt

CD40 is a type I member of the tumour necrosis factor (TNF) receptor superfamily of proteins, and is present on a wide variety of cells including vascular endothelial cells. Ligation of this receptor on endothelial cells is known to increase expression of inflammatory adhesion molecules. We have recently demonstrated that platelets express the ligand of CD40 (CD154) within seconds of exposure to agonist, and...

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Identifiers

PMID: 9869175

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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